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The Other Face of Cancer by Dr Manu Kothari and Dr Lopa Mehta
Cancer : A Perspective
As regards cancer, the common man is at the
mercy of medical man and the press, both thriving on the
paradoxical combination of scare -mongering and
cure-propheysying. Needless to say, the various cancer
societies represent the best, or even the worst of the
above two forces.
The medical double-speak on cancer is not commonly
perceived by the layman. On the one hand, cancer is
described as the greatest bugaboo of man,163
and as a formidable problem almost beyond the
comprehension of the human intellect.164,165 On
the other hand, promises are repeatedly made of the
victory against cancer, promises which have reached their
climax166 with the formation of an agency for
the outright conquest of cancer. A telling
example of medical double-speak may be found in an
authenticated, voluminous recent text 167 on
cancer: In the preface, the editors pontificate that,
Several types of human cancer that were hitherto
fatal diseases have been cured by drug treatment.
Inside, an authority 168 on drug therapy
describes cure by drug therapy as purely
theoretical, since one of the known anticancer drugs has
met the conditions for its full realization.
Due to the persuasive power of the printed word, the
press controls lay thinking on cancer. Describing 14,22,169
cancer as a totally mysterious, totally inexplicable and
total evil, silent preventable killer is commonplace,
occasionally exacerbated by rank paranoia: ... a
savage cell which somehow ... corrupts the forces which
normally protect the body, invades the well-ordered
society of cells surrounding it , colonizes distant areas
and as a final to its cannibalistic orgy of flesh
consuming flesh, commits suicide by destroying its
host.170
Having created needless fears over cancer, the
press then proposes cures for it too. By far the
best defense against cancer is an offense.14
But what kind of an offense? The public has been
oversold, Rutstein lamented:171
Thus, responsible publications cure cancer almost
every week. The pace of cancer research is so
great, the press tells us, that by the turn of the
century cancer will be no more, replacing thus the
Homo sapiens by the Homo longevus enjoying
life without the prospect of death.172 Dawe18
of the American National Cancer Institute thought that
the best analogy of cancer was man himself, proliferating
and plundering. Cancer then will go; cancerous man will
stay for ever!
Who guides the press and how? The scientific community is
educating the press, so that the press can guide the
public.173 For example, every year the
American Cancer Society sponsors science-writers
seminars. These seminars resemble one very long
press conference rather than a series of serious
discussions, boosted as they are by lengthy lunches and
dinners. The Cancer Society apparently believes that
there is a connection between a spate of
"good-news" cancer stories and the success of
its fund-raising drive.173 The Indian
Cancer Society, 169 in a full two page press
release , on February 17,1978, in the style of the
American Cancer Society (see below), declared cancer as one
of the most curable of all disease, only to add that
work is lagging behind for want of funds.
Individual scientists are not exempt from this ploy. A
few years ago, Dr. Robert Good, adorning Time174
magazine;s cover, gave a big story inside it, thus
testifying to his ability to attract research funds
and keep his name before the public.8
Greenberg175 exposed the American Cancer
Societys claim about cancers curability. He44
quoted Davis, the ACS Science editor: Consider the
other major death-dealing diseases among which cancer
rates second: heart disease, stroke, influenza and
pneumonia, diseases of early infancy, diabetes, cirrhosis
of the liver, arteriosclerosis, emphysema, nephritis and
nephrosis. Cancer is indeed one of the most curable in
the country. Yet, cancer is most curable,
because all other leading diseases are more incurable
than cancer. The medical establishment, indeed, never had
it so bad. Despite the remarkable technical
virtuosity of modern medicine, it has made hardly
any change in the adult life expectancy in the USA, in
the last twenty years.176
Confusion worse confounded ! Such may be the
feeling of the reader on perusing the foregoing, and on
perceiving that the earlier chapters of this book, and
the authors larger work The Nature of Cancer,6
are uncompromisingly critical of almost the whole
of contemporary cancer research and cancer
treatment.177
A solution to this seeming confusion lies in a
perspective on cancer, an understanding of it that stands
by us day after day, regardless of the chameleonic nature
of cancer research and reporting. The understanding of
cancer - cancerrealism - apart from offering the delights
of studying cancer as an interesting biological
phenomenon, can also help towards (I) economizing on
cancer, (ii) despecializing cancer, and (iii) accepting
cancer as a facet of life in general and a probable part
of ones own self, in particular. Understanding
Cancer
A Herd feature
Cancer is
remarkably constant as a herd feature. Anybody who
spends a little time brooding over the statistics of
cancer must be struck by their unexpected constancy. From
year to year the figures for each form of cancer show
remarkably little variation. Having so generalized,
Glemser22 cites exact figures: Here
there are 5,355 cases of cancer of the pancreas one year,
5,427 cases of cancer of the pancreas two years later -
almost the same number. Or in another country, there are
218 cases of cancer of the pancreas one year, 221 cases
of the pancreas the following year.
Sir Thomas Browne, the author of Religio Medici,
compassionately opined that the mercy of God has
scattered the great heap of diseases, and not loaded any
one country with all. Cancer occurs everywhere, but
in excess nowhere. A high incidence of cancer in one
organ in a given country gets balanced by a low incidence
of cancer in another organ. Segi and co-workers178
in their report on mortality due to cancer at selected
sites in 24 countries for the year 1962-63, placed
Chile first (among all countries) for carcinoma of the
uterus and of the stomach in females, second for
carcinoma of stomach in males, twenty-fourth for leukemia
in males and twenty- third for the same in females. They 178
placed Israel first for leukemia in males and females,
and twenty-fourth for carcinoma uterus. In the global
scatter of cancer incidence, 179 India
shows the highest incidence of cancer of the mouth,
pharynx and larynx, but is down below the other countries
in the incidence of other cancers.
There are other implications of cancers constancy
as a herd feature. Geographically adjacent countries
present startlingly different statistics. Ireland, barely
60 miles away from England, has 10 times more cancer of
the lip than England, with reversal of the rates for
cancers of lung, breast and uterus. On the other hand,
countries poles apart present comparable cancer incidence
- lethal prostatic carcinoma shows nearly equal incidence
in Canada and New Zealand; women in Scotland and the USA
have similar death rates from carcinoma of the colon and
the rectum.
A large part of the so-called geographic variations in
cancer of different organs is more racial than
geographic. For example, as Khanolkar 180
stated: Now, what is remarkable from a cancer point
of view is that the most common cancer in Hindu women is
a uterine cancer. But with the Parsi women the most
common cancer is of the breast ... Environmentally, their
conditions appear to be the same. What is so interesting
is that we find some cancers more common in certain
groups of people than in other groups living in almost
identical circumstances. While Parsis have a high
incidence of breast cancer, they have an
exceptionally low incidence 181 of other
cancers.
The impartiality with which cancer affects mankind the
world over, the constancy of its occurrence at particular
sites in a country year after year, its startlingly
different statistics22 for
geographically adjacent countries,. and equally
startlingly similar statistics for countries and people
poles apart are all indicators of cancer as an
integral human/herd feature that has nothing to do with
all the postulated cancerogens. The International Agency
for Research on Cancer (IARC) Lyon, France, works on and
publishes continental data on cancer to get clues
to the causation of cancer on the basis of risk
differentials,182 which insimple terms
means an explanation for the high incidence of oral
cancer in India but not in Japan. The IARC fails to
mention that reliable-year-after-year data on cancer in a
country or in a population, and never refers to the fact
that if there are high differentials, there
are compensating low or very low differentials, as well.
Summarizing, one could say that cancer is, even at the
human level, a discernible universal feature that is
independent of the presumed cancerogens, and is impartial
in its global sway. Cancer is a part and parcel of
mankind.
At
Individual Level: Intrinsic, Time-governed, Senescence
Though you
drive Nature out with a pitch-fork, she will find her way
back to triumph in stealth over your foolish contempt.
Horace
Cancer is intrinsic:
The intrinsicality of cancer implies that it is the
individuals developmental programme that determines
whether a cancer would occur. If it is not a part
of his programme, nothing can cause it; if it is, nothing
can prevent it.
Cancer springs from ones own flesh and blood. This
very fact renders the above Horatian aphorism relevant to
human cancer. All therapies put together cannot drive out
Nature, manifesting itself as human cancer.
Cancer is time-governed: Man and animals are
four-dimensional entities, with time as the fourth
dimension. In the words of Portmann,183 animal
life, from its very start as a zygote formed by the union
of the sperm and the ovum, is configured time. Put
simply, all bodily changes of growth and decay occur
along a pre- set programme, the programme unfolding with
the passage of time. It is this time-governedness of
cancer which determines the occurrence of an esophageal
cancer in a boy aged fourteen years, or a man aged
ninety-four years. The time of such occurrence is
normally distributed.
Portmann,183 talking of insect metamorphosis,
observes that the specific formation of the mature
organism is prefigured in the egg, though in what way we
do not yet know, Foulds3 refers to such
pre-programming by animal life as a decision in
advance of performance. Portmann continues: We
have spoken of the insect, but we are all aware that such
temporal processes are embedded in our own life.
Cancer is a temporal process, its programme already
embedded in an individual and manifesting itself on the
aging of the individual. The pre-programming is once
again akin to what Foulds describes as the general
phenomena of decision in advance of performance, both
affirmatively and negatively. The former is exemplified
by a puritanical non-smoker ending up with a lung-cancer
and the latter by a chain smoker smoking his way joyfully
into his nineties without any cancer, of the lung or
elsewhere.
A corollary of cancer being a part of the temporal
unfolding of an individual is that like the
unidirectional time-arrow, it is irreversible. No case of
cancer, despite widespread folklore, has ever fulfilled
the criteria of being labeled as spontaneously regressed
or cured. 184,185
Peregrine Laziosi, an Italian monk who lived from
1265 to 1345 A.D., was supposed to have, in his early
age, a huge cancerous mass on his leg which disappeared
overnight after he desperately prayed to Christ to spare
him the amputation. St. Peregrine, O.S.M., the patron
saint of cancer patients is often invoked for alleviation
and cure of cancer, for which he is best known in
Austria, Bavaria, Hungary and Italy. 186
Can the occurrence of cancer, in an individual, be
advanced in time, by making the body age faster? All
cytotoxic agents - including X-ray and cancer drugs - are
known 187 to accelerate the process of aging
and senescence thus making a cancer appear earlier. Yet,
if cancer is not a part of the individuals
programme, such accelerated senescence of an individual
means the earlier occurrence of the other diseases,
but not cancer. The much-dreaded X-rays (including
those that flow on to female breasts from the widely used
mammograph) do not cause cancer, but make the
cancer appear earlier. In this light, all the so-called
cancerogens are accelerators of a process that is
inherent in the animals,188 a mechanism
discernible from the advancement of the time of cancer
occurrence in animals 188 and humans, 189
and best expressed by the title of an article - Modus
operandi of carcinogens: Mere temporal
advancement.190 There is pithy neologism
for cancerogens - they can be called cancer-preponers.6
Cancer is a form of senescence. In
fact, death is not natural at all. Its really an
avoidable mistake. Fred Stewart191 has
envisioned the discovery of The Methuselah Enzyme
that would desenescence the human body and
make the afore-quoted anti-death hope a reality. With
such an enzyme, the human body just would not senesce.
However, Hans Selye, 192 writing in 1965 on
The Future for Aging Research as the
concluding chapter to Perspectives in Experimental
Gerontology asserted that aging is essentially
an ineluctable manifestation of the entropy that
affects both the living and the non- living , and that
science does not have any evidence to pin its hopes on
some desenescing enzyme. If death is
inevitable and senescence is ineluctable, then surely
there is some basis to link the two: Senescence is the
necessary prelude to an intrinsically-timed ontolysis.
If death is the ultimate function of individual life,
death eventuating processes - cancer, vascular diseases -
assume a physiologic role. Walter Cannon would have
called this the biolytic/ ontolytic wisdom of the
body. Senescence resulting in death is not the
outcome of a loss of programme,193
or a meangingless fade-out of genetic
programming.5 It is an
individual-specific, herd-serving, biolytic programme
that is, for the individual, no less important nor less
purposeful than the biogenic forces that fashion his
being and the biotrophic forces that make him grow and
exert his ability to survive. Why should a purely
chemical process in a substance like collagen which has
essentially the same composition in all mammals, move
faster in some species than in others? ... Senescence
takes a generally similar form in each species, whether
judged by the physico-chemical changes in collagen, the
incidence of degen- erative changes in blood vessels or
the high incidence of malignant disease ... The essence
surely is that there is a genetic "programme in
time" laid down for each species. There must be a
biological clock and a means by which a series of
processes can be made to occur earlier or later according
to the expediencies of evolutionary survival.5
Cancer is but one of a series of senescent forces.
The pantrajectorial occurrence of cancer, from
intra-uterine life to old age in man, has prevented it
from being called a senescent process, as such a process
for reasons etymologic, is expected to occur only in a
senile individual. Senescence has been defined as an
intrinsic process that increases the probability of the
death of an individual. 5,24,193 Cancer, at
whatever age it occurs , is an intrinsic process that
increases the probability of death, whether it be in a
child of two years or in a man of eighty years. In fact,
its function of heightening the probability of death is
more severe when it affects a young individual. In an old
person, multiple, mild or moderate senescent processes
produce an effectively lethal aggregate. Strehler 193
has put down, as criteria of senescence, intrinsicality,
progressiveness and deleteriousness. Now, a child dying
of cancer dies of a senescent process. It dies of a
process that was intrinsic, deleterious and progressive
and which when the child was alive had contributed to the
increased probability of death. Nelsons 194 characterization
of diabetes mellitus as a disease with wide age range -
infancy to old age - during which the disease
may manifest itself, should force us to revise our
thinking on senescence: If cancer and diabetes
mellitus in old age are looked upon as senescent
manifestations of aging, why should not the same in young
age or even in infancy,be considered as anything but
forms of senescence?
Summarizing, the hypothesis that cancer is an intrinsic,
time- governed, senescent process is a gestalt view
on the nature of cancer. The intrinsicness does
not admit of a cancerogen. The temporal nature
accounts for the occurrence of cervical cancer in a young
girl, and in a woman of seventy years; the time-governedness
does not permit regression of cancer, a corollary fully
substantiated by cancerology; the temporal nature allows
the so-called cancerogen to be, more truly, a
cancer-preponer. Cancers senescent nature places it
as one of the numerous pre-death forces; the senescent
nature excludes cancer as being necessarily a lethal
process.
Who
kills Whom?
Foulds3
has deplored the popular usage of military
terminology for cancer, like calling it killer,
slayer, enemy and so on. The compelling reason for not
calling cancer by such epithets is the confounding fact
that, so often, an evident cancer cannot be held
responsible for a persons death. Even in the book
militarily- entitled Seeds of Destruction,195
the very first chapter speaks of the non-role of cancer:
Cancers are generally not in themselves fatal; that
is, with rare exceptions they do not produce toxins or
otherwise kill the host directly.
On the basis of vast survival data of cancers treated and
untreated, Waterhouse 196 was inspired to
suggest that the diagnosis of cancer should not deprive a
person of the benefit of insurance on his life. This
accords to cancer an integral part in ones living,
without pointing at it the accusatory finger - You are
the killer! Patients having cancer, however, do
die, if not of, then with their cancer. Many an
older individual with chronic leukemia dies with
the disease.51 Jones 11 has alluded
to the undefined physiological systems that produce death
of the patient, and along with him or her, of the cancer.
Who kills whom?
Cancer
is Trans-scientific
The liver cell is
more like a typical cell, with no morphological features
that make it extraordinary.197 Yet, it is
an extremely advanced industrial chemical
plant. 198 The liver cell has been cited
here to emphasis the point Smithers 71 made
about the cancer cell - both have no definable structural
entities, and are only organs of behaviour. The
cancer cell goes a step further. Liver cells from
different animals look and behave similarly; cancer cells
dont. Every time a cancer is formed, speciation
occurs - a new species is formed as it were,
unprecedented, unparalleled, unrepeatable.
Cancerologys outstanding limitation is its
ignorance on its leit motif - the cancer cell.
Weinberg 154 calls a question
trans-scientific when it can be asked of
science, but which cannot be answered by science;
such a question transcends science. The causality /
curability of cancer is one such question. Despite its
claims to the contrary, cancerology is a non-science.199
A disease is not an entity .. When the
organism is incapable of resistance, as in cancer, it
is being destroyed at a rhythm and in a manner determined
by its own properties ... Disease is a personal
event. It consists of the individual himself.200
This statement by Alexis Carrel adds a further
individualistic note to the trans-scientific
nature of cancer. Note that Carrel talks of the
organisms destruction, but the manner and the
rhythm are determined by the organisms own
properties. Cancerology thus faces a two-fold uniqueness
- of the individual whose biological trajectory is
predetermined and unpredictable, and that of the cancer.
One more element can be added to this helplessness.
Towards studying the causation of cancer, cancerology has
never been able to cause a cancer when the
cells or the animals had decided otherwise. Whenever it
has claimed to cause a cancer, the fallacy
has been of post hoc, ergo propter hoc.
Given all these crippling limitations, it is easy to
understand why cancerology has not been and will not be
able to do anything against cancer, except studying it as
a biophenomenon. Here lies the saving grace. Cancer, in
many of its facets, is comprehensible, and its behaviour
is predictable at a herd level. Science, etymologi- cally
means knowing, not doing. Cancer is not trans-science if
we aim at understanding it. It is so, if we want to
manipulate it. More correctly , isnt cancer
trans-technique? A part of Homo-sapiens, but not
amenable to the Homo technicus! One more, of the
Illichian Limits to Medicine! 201
Economizing
on Cancer
Scientia est potentia;
knowledge is power. The knowledge that cancer is
essentially non-diagnosable and non-treatable can, as a
concept, propel us towards not doing in cancer.
Munsif , an eminent Bombay surgeon, was fond of
aphorizing that, a good surgeon is one who knows when
not to operate. What medical man needs to learn, in
todays technicalized scene, is when not to
act. This movement towards inaction in medicine is
gaining momentum: Malleson 202 asks: Need
Your Doctor Be So Useless? Illich diagnoses Medical
Nemesis. 201 Lord Platts
autobiography Private and Controversial 203 abounds
in how to avoid modern medicine.
Barbara Culliton 204 has recently reported, in
Science, on the Breast Cancer Detection
Demonstration Project conducted jointly by the National
Cancer Institute and the American Cancer Society,
employing mammography, biopsy and surgery. Pointing out
that mammography may diagnose what it had better not,
Culliton puts a poser: The perplexing question,
misdiagnosis aside, is whether surgery and follow-up
therapy is really necessary. To buttress the above,
Culliton alludes to a study on prostatic cancer, showing
that many a prostatic cancer does not bother its carrier.
The implication is that one would have done these
men no favour by treating them for a disease that was not
causing them any problem. A paragraph from the
authors book on cancer, 6 published in
1973, deserves repetition here. Doing nothing -
neither diagnosing nor treating unless compelled by a
cancerous patients dis-ease - is the highest form
of non-empiricism, non-arbitrarism, a kind of I-respect-you-
(the patient)-and-Nature creed. It is refusing to interfere
backing the refusal by a well-deserved assurance or
discreet resignation. Agreed that there is never
nothing to be done,165 but this
"never nothing" should be , whenever warranted,
a Jeffersonian "pious" fraud. It cannot be
overemphasized that a doctor is an adviser first
and foremost, a doer only when the situation
dictates. Should a patient ask him whether the former
could be a Ulysses 205 in the world of medical
investigations, get killed by chemotherapy, or fall off
the Golden Gate Bridge, the doctors advice should
be an assertive "No", for which the patient
should neither deny him his fees nor drag him to the
court of law.
The realization that the path of Mary ( one of
contemplation and inaction) is preferable to that of
Martha 206 even in cancerology, can mean a lot
of saving on the psychic / somatic human cost, on animals
and as a payoff from these on the hard cash spent on the
overall problem of cancer.
Sparing
the Human Psyche
The EKF (ECG)
machine, a cardiologist commented, has done more harm
than the atom bomb. The harm is in terms of the cardiac
neurosis that the machine breeds. Christiaan Barnard 207
talks of the EKGs (ECG) electrical
squiggle transforming happy individuals with a
purpose in life, into frightened, unhappy creatures of
despair.1 Harrison 208 remarks that physicians
suffer from EKGitis, and Heaven help their patients.
Kraus 209 rightly said that Diagnosis is
one of the commonest disease. Marcel Proust 210
lamented that for one disease that doctors cure,
they produce a dozen others in healthy individuals by
inoculating them with an agent a thousand times more
virulent than all the bacteria in the world, viz.
the idea that one is ill. Iatrogenic (iatral)
diseases, it is commonly believed, 211, 212, 213,
can be produced only by treatment it needs to be
appreciated that diagnosis itself is an iatrogenic
disease.
Diagnostically produced dis-ease is a major problem in
cancerology. Despite the fact that the Pap smear, as of
today, had doubtful 214 utility towards
diagnosing / preventing cervical cancer, the Pap industry
flourishes. The terms employed by the cervicologists are
indiscreet, to say the least. In a series in which no
definite cancer was found, the article had the title
Positive cancer smear in teenage girls,
215 and carried an exhortation: A description
of the findings in seventy-seven girls who were less than
twenty years of age when they were first discovered to
have a positive cancer smear should support the
contention that no age limit can be imposed on the
application of the cancer screening method: if a girl is
old enough to have a vaginal examination she is old
enough to have a cervical cytologic examination. Is
this not diagnostic vehemence, diagnostic iatrogenesis?
The problem is no different for the breast, as Culliton 204
found (see above). All this diagnosing breeds what
Kind 216 calls iatrogenic non-disease,
wherein the physician treats his patient for a disease
which he has diagnosed but which does not exist. What if
it does? We have by now been able to evolve an
understanding that if the cancer does not dis-ease,
nothing, not even diagnostics need be done, thus saving
on all the investigations that otherwise necessarily
follow.
Sparing
the Human Soma
Having made a
diagnosis, treatment is not a must. If the cancer
dis-eases, the minimal need be done. Today, mere
lumpectomy is followed by results as good as those
obtained in breast cancer after radical surgery.6
Such minimal therapy is applicable to other cancers -
prostate, 217 stomach, 140 pancreas
218 and so on.6 Cancerologists are
not exempt from treating people as things, to
earn more money. Over 190 years, 103 cancer
operations were done more for personal gain than for the
patients benefit; things are not altogether
different now.219 The amount of
unnecessary surgery219 today
vindicates Shaws attack on the
pecuniary interests of the surgeons. Surgeon,
heal thyself!
Besides the mundane consideration of money, of greater
importance is the sheer physical price that the human
body must pay every time therapy for cancer is given.
Doctors, a cancer- patient-turned writer
complains, play God with my body and life. 220
Surgery, of necessity, mutilates; chemotherapy and
radiotherapy destroy many a normal cell before killing a
cancer cell; harmone therapy can mean earlier death from
cardiovascular disease, 217 immunotherapy can
mean the worsening of a cancer. The one dictum that all
therapists can safely follow is - Less is more.
Cancer nostrums are big business. They thrive
because truly effective drug therapy had not yet been
achieved. 221 When nothing really
works, everything can be supposed or shown
as working against cancer; and hence the current
Laetrilomania. 222 Laetrile, or
the anti-cancer vitamin B 17, is condemned as
being neither anti- cancer, nor vitaminish, but a
money-making fraud, that is at best an expensive and
cruel hoax, and at worst dangerous. 220, 223 Laetrilomania
is a classic illustration of peoples faith that something
can always be done against cancer. The breeders of this
faith are the leaders and the institutes interested in
cancer research who, now and again, overwhelm the
public with electric-guitar-like- clatter in extolling
the progress of conventional cancer research.222
Sparing
Animals, Cutting Down Research
Not one
causeof human cancer has been found by animal
experimentation,18 not one cure either.6,23
All that the study of cancer in animals teaches us
is that the ways of cancer are as protein as
the ways of life in all its forms.224 The SPCA
would be fully justified in asking for cutting down of
research on animals, on incontrovertible cancerological
grounds.
Cancer research is what anybody does anything in
the sophisticated field of genetics and molecular
biology.15 An editorial 225 in the
BMJ posed a question - How relevant is present
cancer research? The editorial asked for an
agonizing appraisal since it was becoming
clear that money spent on cancer was going down the
drain. Smithers 71 characterized cancer
research as a great field for gathering bric-a-brac,
one that has lacked not funds but direction. A piece that
appeared in The New York Times, 226 in
a way, typifies cancer research; A controversy has
arisen over a prominent researchers purpose in
conducting an experiment, in which he induced cancer in a
small group of rats. The Federation of American
Scientists, a public interest science group has charged
in its monthly newsletter that the scientists conducted
the tests merely to make a satiric point. The scientist,
Dr. George E. Moore of Denver General Hospital, produced
the cancers by inserting sterilized dimes into the
peritoneal cavities in the rats abdomens. Dr. Moore
and his collaborator, Dr. William N. Palmer, published
their findings in August in a letter headlined, "
Money causes cancer; Ban it."
Cancer research as yet has meant, to use Arleys
words, 227 that more people live on cancer
than die of cancer. What else could it be, given the
odd mixture of the Promethean zeal, the cancerophobia,
the politicization of cancer. I believe , however,
that one might justly summarize American medicine as
being based on the maxim that what can cure a disease
condition in a mouse or a dog can, with the right
expenditure of money, effort and intelligence, be applied
to human medicine. What Burnet 228 says
about the USA, can be extrapolated to any other country.
The Cancer Research Institute in Bombay,founded in 1952,
is a grant-in-aid-institution, under the Atomic Energy
Establishment, Government of India. The five- storey
building has most things that a cancer institute would
have. In a multi-coloured handout, meant for lay
consumption, it gives all adulatory details including
information on the Philips EM 300 electron microscope
providing a magnification of up to 200,000 times for the
study of normal, precancerous and cancerous tissues.
Science is supposed to be the human search for truth.
Should not the institute have declared for once that like
elsewhere in the world, all that the electron microscope
has done against cancer is to magnify 200,000 times the
human ignorance on cancer?
Fundology
of Cancer
The
hypothesisis unencumbered by any supporting evidence.
The budget is the only part of the application which
seems to
have any substance whatsoever.
Anonymous
The above comment by a
member of the National Institute of Health (USA) study
section, on an application for funds, exemplifies what
Hixson8 found out about cancerology - when
ignorant of what to do, ask for more funds. There is
the whole science of getting funds: 8,23, 229
fundology is a good name for it. Faculty are
immersed in administering the grants acquired, and their
prevailing literary exercise is the writing of grant
proposals. In short, the academic life has become one not
of reflection, but of action.230 An
unwritten law guiding the above literary exercises is to ask
for more, spend more than you have asked for and thus
assure for yourself a greater and greater grant every
next year. In science today, a man gets
known by the finds he begets.
The annual outlay, in the USA, for cancer research
will soon reach the 1 billion dollars mark, and will have
to be increased at the rate of at least 100 million
dollars a year just to keep pace with inflation.231
Money is where cancer is. Cancer has pizzazz, luncheons,
theatre parties fund-raising luaus, glamour, and in
actual dollars and prestige, even heart/mental
disease cannot hold a candle to it.232 Berman 232
points to the biggest risk in this game - what will
they do if a cure comes out of it? They need not
worry; cancer will not let them down. Public
understanding of cancer may.
There is the world of cancerology the all too common
human failing of keeping up with the Joneses. A linear
accelerator acquired by one institution is soon put to
shame by a bigger accelerator at another. Berman 232
describes how, when something happens to a bigwig,
institutes jump in to make capital out of it. The
President of India, Sanjiva Reddy, was discovered to have
a lung tumour. With the usual fanfare he was flown to the
Mecca of cancer research - the Sloan-Kettering Institute,
New York. Somehow, the Government of India was made to
understand that this had to be done, because India
didnt have a linear accelerator. India already had
one, working. Someone protested, but his voice was
drowned in the din of the Establishment. The
Presidents illness is expected to leave the legacy
of the prestigious linear accelerator to the major cancer
centres in India.
The U SA spent 15 billion dollars directly or indirectly
on cancer for the year 1968.233 In 1994 the
total bill for health care is expected to exceed billion
dollars a day.234 Surely, a sizeable part of
this must be for the diagnosis, rediagnosis, treatment
and retreatment of cancer. Perhaps the USA can afford it.
But what of India, Pakistan or Egypt where the majority
live below the poverty line? Many an Indian, capable of
leading a useful life for himself and his society, goes
begging for treatment - be it for tuberculosis, leprosy,
chronic poliomyelitis - for want of funds, while cancer
research and treatment, with all its sophistries, go on
at the major centres in Bombay, Delhi, Calcutta and
Madras, where they toe the line drawn by the affluent
West. The Indian Cancer Society 169 itself, in
its birth, was inspired by the monumental service
rendered by the American Cancer Society. No wonder
we are out shopping for linear accelerators!
Despecializing
Cancer
There prevails in
specialized institutes an air of we-know-
everything-about-the-disease. Such arrogance is the
outcome of a constellation of factors - (I) after all,
specialization is the order of the day, (ii) being specialized,
the institute and its men are most sought after from
within and without the country, (iii) the diseasophobia
gets tactfully built up by the institute, its peripatetic
men, and the affiliated societies, and (iv) the
Governments and the publics gullibility is
that more funds to a specialized institute makes for more
cures.
The outcome of the above specialized-institute-syndrome
is twofold: (a) the inevitable
wiser-than-thou attitude of the specialists
who let the people know their designations and degrees
tactfully through the media, and (b) the long waiting
lists for an appointment, admission, operation, with the
resulting humiliation, sense of despair, anxious-waiting
on the part of the patients and their relatives. Our
concern here is with the latter point.
With cancer, the most feared name among diseases, it is
natural that people seek the speciality centres. Over the
year we have witnessed commendable and voluminous
therapeutic work on cancer done by non-specialized
general hospitals. The specialized cancer
centre in Bombay, the Tata Memorial Hospital does less
work on brain cancers than the general
hospital ( to which the authors are attached) with a
neuro-surgery department that has become a referring
centre for brain cancer cases, even those from outside
Bombay. That is not all. The diagnostic, histopathologic,
and autopsic studies on cancer in general hospital are
also significant. What is most important however, is the
fact that a cancer case treated in a general hospital,
fares no worse that when treated at a specialized centre
- a truth that allows global verification. Let us
despecialize cancer for the following reasons :
- Cancer therapy is
lumpology. A cancer therapists
chief function is to see a lump, to excise it by
surgery and / or reduce its bulk by X-rays,
drugs, or hormones.
- The diagnosis of
cancer, i.e. the detection of the
cancerous lump/s is on the basis of clinical
examination and investigations which are not
outside the functioning potential of a general
hospital.
- Surgery forms the
mainstay of cancer therapy and can be competently
performed in most well-equipped general
hospitals. What a cancer patient wants is the
necessary diagnosis and
therapy without loss of time.
Despecializing cancer would help achieve this.
How do we despecialize? The answer is simple:
Tell the people the truth that it is not
important who treats and where, but who and what
is treated.
Accepting
Cancer
The contemplation of
things as they are, without substitution
of imposture, without error or confusion, is in itself a
nobler
thing than a whole harvest of inventions.
Francis
Bacon
Bacons invocation is
pertinent, both for the cancer doctor and the cancer
patient. The very term contemplation carries with
it the message of the need for humility, patience, and
restraint. To understand cancer is to accept cancer, with
grace.
Cancer may easily be accepted as a part of mankind, but
what when it comes to ones own self? Somebody has
shown the way out.220 Jory Graham, who has
lost both her breasts to cancer that spread to her
vertebral column and legs, took to writing a column
inspiringly titled A time to live .. . for
the readers of the Chicago Daily News / Sun-Times. Like
other cancer patients, her first reaction was, Why
me? Graham sought the answer in the existentialist
creed that the universe as such is absurd and that her
cancer was simply random luck. The three
italicized words would have pleased Blaise Pascal, were
he alive today; he would have realized that someone could
adopt his probability child even when confronted
by a personal tragedy. With such an approach, Graham
changed her question: Why not me? And with
that came a sense of power,. a realization that in the
time left, she could still make choices and
decisions. Graham lived with her cancer, and what
is more, she inspired others to do so.
Cancer
Can Be Lived With
I submit that patients
with cancer spend many more patient-
years living than dying. There is really much more that
could
have been said about the patient living with cancer, and
dying
is certainly not the sole province of the person
afflicted with
cancer.
Charles
Tashima 285
A favourite theme of Sir
William Osler was to live in daylight compartments. He
epigraphed on e of his addresses with the words of Robert
Louis Stevenson:
Contend, my soul, for
moments and for hours;
Each is with service pregnant, each reclaimed
Is like a kingdom conquered, where to reign.
Osler did not direct his
positivism only to some cancer patients for whom
time is running out. He, like Kipling and
Stevenson, pleaded that time is running out for everyone
afflicted with an incurable disease called
life. And since everyone so incurably
afflicted with a killer disease - (The aim of all
life is death.)36 - lives, there is no
reason why the presence of another killer disease, e.g.,
cancer, should mar an individuals zest for living,
his joie de vivre. The title of Barnards
book HEART ATTACK -You Dont Have to Die 207
can be altered and enlarged to read as CANCER - You
Dont Have to Die While You Are Alive. Despite
affliction with a killer disease, it is possible to live
long, be married, remarried, produce children, write
medical textbooks, write soul- stirring,
Nobel-prize-winning novels, and to make, like Louis
Pasteur, epoch-making medical discoveries. And all this
despite the inescapable impotence of medicine, so that
the foregoing must be taken as evidence of the poorly
appreciated benignancy of the so- called malignant
diseases.
William Boyd,51 the pathologist-author, had,
in 1948, at the age of 63, mucus-cell adenocarcinoma of
the parotid. For more than a quarter century thereafter,
the medical world remained rich with Boyd himself and his
books on pathology. His 1970 (eight) edition of A
Textbook of Pathology51 was a book of 1464
pages, 908 illustra- tions, and a superb updated text.
Alexander Solzhenitsyn had cancer in the mid-1950s from
which he recovered. But the cancer has not dried up
Solzhenitsyns pen nor has it deprived him of a
marriage thereafter to Natalya from whom he has two sons.
And, let us note, all this and a Nobel prize, too, for
literature despite a killer disease over decades ago.
He has endured, writes Foote 235 while
reviewing Solzhenitsyns August 1914,
slave camps and near death from cancer. His
experiences seem to have produced a strong belief in the
existence of an inextinguishable sense of justice in
human society and - despite the power and prevalence of
evil (and cancer) - a spark of absolute conscience in the
individual.
Sigmund Freud had two killer diseases a coronary
thrombosis in his 30s and an oral carcinoma is his
60s. And yet, these two enemies within could not
kill Freud who had to be helped to death by a friend,
his physician / friend Max Schur who twice injected two
centigrams of morphine to put him into a peaceful
sleep, for ever. In all Freud had 33 operations
performed on him for his carcinoma. And yet he lived
up to the end: His ability "to love, to give,
to feel, stayed with him to the end," and his
creativity endured; in his last years he wrote some of
his most significant papers, none of them noticeably
influenced by his illness.36
This refusal to stunt ones modus vivendi
was shown equally well by Francis Weld Peabody. Peabody
was in the last stages of malignant disease
and was taking a round of his ward when, to conserve
Peabodys energy, his house officer suggested that
he might pass by the next patient, who had a
typical pneumonia of the right lower lobe.
And the inexhaustible Peobody roared: Of course, I
shall examine the patient and listen to his chest;
although I have auscultated thousands of lungs I have
never heard two which sounded alike.236
Peabody died in 1927, but in the same year he published
an important paper on pernicious anemia in the American
Journal of Pathology.237 It was fairly
soon after his marriage to Laura that Aldous Huxley
developed a metastasizing carcinoma of the tongue. But
the killer disease could not kill the
philosophers joie de vivre and he so lived,
thought, and wrote that Laura Archers Huxley could write
a moving biographical account of her husband, entitled This
Timeless Moment 37 - a message capable of
enlivening every moment of every man.
We have talked so far only of celebrities; we may also
draw lessons from the lives of some ordinary men.
Sanghavi, the father of a microbiologist and the
father-in-law of a consulting physician, of Bombay, was
operated upon in May 1967 for a carcinoma of the lower
third of the esophagus, which, in the words of Boyd, is
one of the most hopeless conditions. With the
nodes involved, guarded prognosis was given.
In the post-operative period, Sanghavi developed
retention of urine from an enlarged prostate for which a
prostatectomy was done on him in September, 1967. From
that day, till March 1980 and aged 73, Sanghavi did not
look back; he ate well, attended to his work, and but for
tell-tale operative scars, was as normal as anyone else.
The other case is of Dr. Adenwalla, a general
practitioner who was operated upon in 1961 for a colloid
carcinoma of the cecum. Following the hemicolectomy, Dr.
Adenwalla continued to practise till his death in 1984.
In 1971 he was most satisfactorily operated upon for a
carcinoma of the large bowel. Yes, it is possible to be
struck by a killer disease twice, and yet to be able to
refuse to say die.
The border-line between sympathy and pity is very
narrow, writes Newton-Fenbow,238
and pity is corrosive. It must be realized
that the scare-mongering of modern medicine has created
pitiable stigmata out of the so-called killer diseases.
Diagnose cancer, coronary heart disease, or hypertension
in an individual, and society starts looking at the
individual with pity" Dont do this;
dont do that. If one only makes a
determined effort towards normality when one has to ,
then one finds (thank to the pitiers) an increasing
number of very valid reasons why today no effort should
be made but tomorrow - and when tomorrow arrives one is
finally incapable of making any effort.238
It is the duty of the physician to spare his patient the
burden of paralyzing pity and confusing dos and
donts from the humans that surround him.
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